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Using themselves as subjects and RIA, they demonstrated that people experience higher insulin levels when they eat sugar than when it is injected into their bloodstream (McIntyre, Holdsworth, Turner)
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National Institutes of Health, Bethesda, MD, USA)

Chronic treatment of JTP-109192, a novel G-protein coupled receptor 119 agonist, improves metabolic abnormalities in Zucker Fatty rats

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The result is a drug that reduces how much you eat, improves how your body processes sugar, and increases how many calories your body burns, all at once