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A third major risk is dosing

While ROS play essential signaling roles and help regulate cellular redox status, their over-accumulation disrupts cellular integrity, leading to lipid peroxidation, protein degradation, nucleic acid damage, and ultimately cell death

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The dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide: a novel cardiometabolic therapeutic prospect

doi: 10.1016/j.gendis.2019.09.006

S100-A9 protein in exosomes derived from follicular fluid promotes inflammation via activation of NF-B pathway in polycystic ovary syndrome