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it often depends upon a high index of suspicion engendered by the finding of failure to thrive and Fanconi syndrome

Therapeutic strategies targeting Ferroptosis involve controlling lipid peroxidation, manipulating thiol metabolism, and regulating specific miRNAs and heme oxygenase-1
These nitrated mitochondrial proteins give rise to mitochondrial DNA damage and the opening of the mitochondrial permeability transition pore (MPTP), eventually inducing cell necrosis (Figure 2)

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