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while respiratory viral infections cause antioxidant enzyme expression/activity inhibition associated with reduced Nrf2 nuclear localization, decreased cellular levels and reduced ARE-dependent gene transcription (Komaravelli and Casola, 2014)

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Aged mice also exhibit more prolonged fibrosis after a single dose of bleomycin than young mice do, and inhibition of NOX4 inhibits fibrosis persistence in aged mice

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Cys 2 ), cystine-free (Cys 2 -free), or cystine-free supplemented with GSH (750 M), CysGly (750 M), Fer-1 (10 M), or Trolox (100 M), and relative cell numbers were determined (n = 8 technical replicates from 2 independent experiments)