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fluid build-up in or around the lungs - pain when you breathe, feeling short of breath while lying down, wheezing, gasping for breath, cough with foamy mucus, cold and clammy skin, anxiety, rapid heartbeats
One mechanism which could lead to these properties was suggested to be the binding of beta-3-adrenergic receptors located on white fat and thus increasing the rate of metabolism in fat cells

United Kingdom National Quality Assessment Scheme for Haematinic Assays (UK NEQAS), 18 February 2014
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The definition of vitamin B 12 (cobalamin) deficiency varies with the assay used