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doi: 10.1200/JCO.2021.39.15_suppl.e14513 82 Collinson-PautzMRChangWCLuAKhalilMCrisostomoJWLinPYet al

Endocrinology 2002, 143, 18511857

Bundesen, L

Meanwhile, activated microglia can be converted into M1 (pro-inflammatory type), releasing a variety of deleterious substances such as interleukin-1 (IL-1), TNF- , and reactive oxygen species (ROS) into the circulation (Perego et al., 2011), and these pro-inflammatory factors can recruit leukocytes to the site of injury, exacerbating brain damage and leading to cell death (Figure 1)

Bisulfite sequencing is still currently the gold standard method for detecting DNA methylation in patients with cancer [8]
