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Feng W, Shi W, Wang Z, Cui Y, Shao X, Liu S, Rong L, Liu Y, Zhang H

However, in DMT1-mutant models, this recycling pathway is disrupted, leading to iron sequestration in lysosomes in a redox-inactive form, thereby lowering cytosolic Fe 2+ levels and suppressing Fenton reactiondriven oxidative stress and ferroptosis

Biochem Pharmacol 38(23):41774182

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Shiao SPK, Grayson J, Yu CH, Wasek B, Bottiglieri T

Right atrium This 76-year-old man presents with episodic palpitations, light-headedness, dyspnea, and fatigue in the setting of chronic alcohol use disorder
