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GSH regulates antioxidant defense, growth, death, immune function, and fibrogenesis

Future efforts should focus on developing multi-scale integrated models, combining single-cell omics to construct spatiotemporal maps of polarization signals, enhancing the application of deep learning in cross-scale mechanistic exploration, and employing virtual screening platforms to predict nanomaterial-immune cell interactions, ultimately advancing precision clinical translation targeting macrophage polarization

Efficacy and safety of rontalizumab (anti-interferon ) in SLE subjects with restricted immunosuppressant use: results of a randomized, double-blind, placebo-controlled phase 2 study

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These compounds are typically distributed as research-grade substances, meaning their extended safety data in non-clinical populations remains incomplete

It was found to have antioxidant effects by increasing glutathione concentrations, which are reduced in COPD [90]