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Research shows that nutrition is critical to healthy development during puberty
Worryingly, the worldwide prevalence of obesity continues to increase and has tripled since 1975, with 1.6 billion overweight adults and 650 million obese adults [3]

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Until more research is available, the use of these drugs in T1D should be done carefully, with a thorough discussion with patients about potential risks and benefits of this approach

In this study we employed structure-based site-directed mutagenesis together with pharmacological assays to compare agonist efficacy across two key signaling pathways, cAMP accumulation and ERK1/2 phosphorylation (pERK1/2)

doi: 10.1038/s41598-019-52103-x [DOI] [PMC free article] [PubMed] [Google Scholar] 132