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Bonaca MP, Catarig AM, Houlind K, et al

Dallman et al., 2005

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WD increased weight gain and plasma leptin levels and reduced PSD95 in the amygdala in both sexes, whereas GE2 treatment induced weight loss, elevated plasma PYY levels, and improved associative learning in both sexes

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As you lose weight, the dose you need may change, especially for beta-blockers and calcium channel blockers, which also lower blood pressure
