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268 Inflammatory cytokines (e.g., IL-6 and TNF-) upregulate the expression of CYP24A1 in colon cancer cells by activating the NF-B pathway, which in turn leads to abnormal activation of the Wnt/-catenin pathway and promotes disease progression

This combined mechanism produces substantial reductions in appetite, caloric intake, and body weight, as demonstrated in phase 2 clinical trial data published in the New England Journal of Medicine

According to the American Diabetes Association (ADA), those with diabetes should lean into low-glycemic foods that are high in protein naturally, packed with gut-friendly fiber and provide healthy fats

The injectable form (Ozempic) was first approved by the FDA in 2017

Zhao Y, Yang H, Wu P, Yang S, Xue W, Xu B, et al