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As AP-5 abolished tGLP-1s effects on vasopressin, this suggests that GLP-1s effects on arginine-vasopressin neurons may be mediated through NMDA receptors

This chemosensor, together with other 27 non-selective cationic channels, is part of a larger family named transient receptor potential (TRP) channel superfamily and is known to play an important role in the metabolic syndrome (361, 362)

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Staying well-hydrated is essential, particularly if experiencing vomiting or diarrhoea, as dehydration can lead to acute kidney injury in severe cases