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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily used to manage type 2 diabetes and, in some formulations, to support weight management

doi:10.1097/ADM.0000000000000249

For FDA-approved tirzepatide The LillyDirect Zepbound Self-Pay Journey Program starts at $299 per month for the starting dose and $449 for maintenance doses

Qsymia The price of Qsymia ranges from $240 to $300 per month for a 30-day supply, according to GoodRx

For maximum effectiveness, retatrutide may surpass tirzepatide but is not yet FDA-approved

Specific variants in these pathways can influence receptor sensitivity, medication clearance, and side effect susceptibility