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It occurs when the pair of nerves that connects the brainstem to the gastrointestinal tract (vagus nerve) is damaged or not functioning properly.

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We don't have good data on: *What outcomes look like at various sub-therapeutic doses *Which patients might benefit from lower, more frequent dosing versus higher, less frequent *How hormonal changes (hello, perimenopause) affect optimal dosing *Long-term effects of maintenance microdosing after weight loss goals are met The doctor quoted in the article is right that standard doses exist because they've been proven effective

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In these women, the chance of delivering early was roughly 911%, about 7084% higher than those not on GLP 1

Although these mechanisms have been exploited to facilitate weight loss, these medications have also been indicated for patients with cardiovascular or renal diseases, all of which have caused a recent drastic rise in prescribing GLP-1 RAs