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Unlike males, only females whose onset age of smoking was earlier than 20 years had a higher risk of developing UC compared to female non-smokers

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[25] Early cultivation of tobacco [edit] In the first few years of tobacco cultivation in the colonies, the plants were simply covered with hay and left in the field to cure or "sweat." This method was abandoned after 1618, when regulations prohibited the use of valuable potential animal food for such purposes

The adult beetles can live for up to two months, while the larvae stage can last for several weeks before pupating into adults