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[ 423 ] BACH1 transcriptionally enhances FOSL2, thereby inducing the M2 macrophage phenotype through activating the TGF/SMAD signaling to facilitate the transformation of lung fibroblasts into myofibroblasts, and BACH1 deficiency alleviates BLMmediated pulmonary fibrosis

[Google Scholar] Cohen E, Paulsson JF, Blinder P, Burstyn-Cohen T, Du D, Estepa G, Adame A, Pham HM, Holzenberger M, Kelly JW, Masliah E, Dillin A

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The first involves the interaction between one molecule of H 2 O 2 and CAT which leads to the production of Compound I, in which the heme group is oxidized to oxyferryl species [45, 50, 52]

Front Physiol 2018;9:1094

Gastroenterol., Gepatol