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Genetic recombinant experiments were reviewed by Safety Officer in RIKEN, and approved by the director of RIKEN Wako Campus (approval number: 2022-029(1))

In addition, the improvement of liver function markers such as ALT, AST, and ALB reflects the enhancement of liver synthesis and metabolic capacity, which directly contributes to improving overall health and reducing disease burden

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Pargalija D, Klinkenberg M, Dominiguez-Bautista J, Hetzel M, Gispert S, Chimi MA, Drse S et al

For instance, pachymaran (PCP), the major constituent of Poria cocos , activates the Nrf2/ARE pathway, upregulates HO-1 and NQO1 gene expression, enhances intrinsic antioxidant capacity, and suppresses TLR4/NF-B signaling to reduce inflammatory mediator release (70)

Thiol oxidase activity of copper, zinc superoxide dismutase