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[DOI] [PubMed] [Google Scholar] 46.Clarke J.D., Hsu A., Yu Z., Dashwood R.H., Ho E
Typically isolated from cell cultures by removing cell debris through centrifugation, exosomes are of particular interest in drug delivery due to their biocompatibility and capacity to carry various bioactive molecules [451] For exosomes to be effective in brain drug delivery, they require the incorporation of ligands that facilitate RMT across the BBB, as without such ligands, their capacity for BBB penetration is inherently limited [11]
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A total volume of 2 mL at 10 mg/mL protein concentration was loaded for size estimation
