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For men who do not respond to oral medications, second-line treatments include vacuum erection devices, intracavernosal injections (alprostadil), intraurethral therapy, or penile prosthesis surgery

outcomes are not certain

For small molecules, refer to ICH guidance S2(R1) for recommendations on genotoxicity testing, which does not apply to biologics.9 Initially, a gene mutation assay (e.g., in vitro Ames test) will support a singledose trial

First, they often dont work on WiFi hotspots, which youre likely to be using when away from home

Open randomized multicenter study to evaluate safety and efficacy of low molecular weight sulfated dextran in islet transplantation

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