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Calcium released in the cytoplasm causes cytoplasmic PKC to translocate to the plasma membrane while calcium that is released within the nucleus translocates nuclear PKC to the nuclear envelope.79 Also, there are separate pools of DAG produced by phospholipids localized within the cytoplasm or the nucleus.80 Furthermore, stimulusdependent production of DAG leads to selective translocation of specific PKC isoforms to the nucleus

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Nuclear acetyl-CoA production by ACLY promotes homologous recombination

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