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Other contributors to this work include Premranjan Kumar, Chun Liu, James W

doi: 10.1039/b811723c

The thermal shock from cold liquid hitting lyophilised powder can cause localized crystallization that reduces solubility

Mechanism of lipoic acid in the treatment of metabolic dysfunction-associated steatotic liver disease In preclinical studies, LA has been shown to improve nonalcoholic fatty liver disease by modulating a variety of molecular pathways

Kou et al

Talanta 81, 13001309