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Description
The PERK pathway intersects with the integrated stress response (ISR) at eIF2 phosphorylation PERK is a type I transmembrane ER protein containing a luminal domain similar to that of IRE1 and a cytosolic S/T protein kinase domain
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Gerke AK, Hunninghake G
Kamolz, T., Pointner, R
Moreover, in line with the role of BHB in supporting OXPHOS in CD8 + T cells 31 we observed similar metabolic changes when human (but not mouse) CD8 + T cells were cultured with BHB (Extended Data Fig
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