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The promising effects observed in vitro often require sophisticated formulations (e.g., with piperine, nanoparticles) to be partially translated in humans, raising questions about the efficacy of simple dietary intake or standard extracts (50)

The consequences of HNE binding to proteins in neurons and glia are to change their conformation and lead to significant diminution if not loss of functions (1621)

TLN showed desirable size ( 7 nm) with the ability to load high concns

METTL16 inhibits papillary thyroid cancer tumorigenicity through m6A/YTHDC2/SCD1-regulated lipid metabolism

Although omics profiling has substantially expanded our understanding of these processes, much of the literature remains single-layer, making it difficult to distinguish causal biology from timing, protocol, and tissue-composition effects