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81,86 Established Modifiable Risk Factors Atherosclerosis and the early phases of cardiovascular disease often begin early in life and progress slowly over decades

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Some studies suggest that OCTN1 mediate the uptake of a mushroom metabolite named ergothioneine, which probably exerts an anti-oxidant function in tissues exposed to ROS (Pochini et al., 2012, 2016), a ubiquitous pathway that modulates several cell functions, among which inflammation (Pochini et al., 2015, 2016)

Large-scale RCTs, refinement of more palatable diets and other nutritional ketogenic strategies are needed to optimize nutritional ketosis in clinical practice as a non-pharmacological treatment strategy in epilepsy

As a result, finding adjunctive treatments to help with fatigue in those with hypothyroidism is needed
