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The APOE3 -Jacksonville ( APOE3- Jac) mutation on an APOE3 backbone results in a Val to Glu substitution at position 236 within the C-terminal domain (Fig

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Novel therapeutic strategies involving mesenchymal stem cells and their derived exosomes, gut microbiota modulation, bioactive compounds from traditional Chinese medicine, and AI-assisted disease management systems offer promising approaches to correct molecular dysfunctions

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