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Together, these strategies aim to establish a closed-loop framework linking mechanistic insight, targeted delivery tools, and clinical validation, accelerating the translation of ferroptosis-based interventions toward precision treatment in AD

In ENS, neurotransmitters nitric oxide (NO) and vasoactive intestinal peptide (VIP) are considered to play important roles in the maintenance and protection of neurons (Sandgren et al., 2003)

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Here's a before and after to show you the end result

doi: 10.1016/j.autrev.2014.10.016 5 BelvoncikovaP.MaronekM.GardlikR