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In metabolically dysregulated adipose tissue, NNMT is overexpressed and consumes large quantities of SAM
Treatment typically requires intramuscular hydroxocobalamin injections (1 mg three times weekly initially, then every 23 months lifelong) when malabsorption or neurological symptoms are present
Nearly three million people in the U.S
in others, it appears to have a genetic component
Thigh: The front or outer thigh provides another reliable option
