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To prolong the effects of endogenous dopamine and exogenous levodopa, adjunct therapies are used to block dopamine metabolism in the central nervous system

Biochem J 1998

ROS have been implicated in a number of pathologic processes, including reperfusion injury, cancer, inflammatory disease, and aging

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Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL. Glutathione dysregulation and the etiology and progression of human diseases. Biological Chemistry. 2009;390. doi:10.1515/BC.2009.033

The Role of the Dysregulated JNK Signaling Pathway in the Pathogenesis of Human Diseases and Its Potential Therapeutic Strategies: A Comprehensive Review