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Given that cuproptosis preferentially targets OXPHOS-dependent cells by disrupting TCA cycle enzymes and Fe-S cluster integrity, 167,213 it remains an open question whether GSH-dependent Fe-S cluster biogenesis similarly licenses susceptibility to cuproptosis

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Bertoli S, Leone A, Vignati L, et al

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Pain is typically the main symptom, but other symptoms may include depression, anxiety, sleep disorders, and various other conditions

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