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Vui MR, Baoi R, Mitrovi J, Petrovi M, Velinov N, Kosti M, Boji A (2021) Comparison of the advanced oxidation processes in the degradation of pharmaceuticals and pesticides in simulated urban wastewater: Principal component analysis and energy requirements

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Cancer 10 (7), e004147

Both the SWI/SNF inhibitor AU-15330 and the mitochondrial complex I oxidative phosphorylation inhibitor IACS-010759 showed pronounced synergy with bi-steric mTORC1 inhibitors to cause cuproptotic cell death in RP/MRD cells, suggesting these combinations as a potential patient treatment strategy for rapalog resistance