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192 Additionally, mRNA therapy has been applied to treat patients with deficiencies in essential enzyme genes, such as argininosuccinate lyase, ornithine transcarbamylase, and methylmalonyl-CoA mutase (MUT), therefore restoring enzyme levels and mitigating deficiencies

doi: 10.1016/j.freeradbiomed.2005.12.032 77

Rhamnetin has emerged as a promising compound that can disrupt this angiogenic switch by targeting these critical factors and signaling pathways, effectively inhibiting tumor vascularization and growth [82]

While all four ORFs caused mitochondrial fragmentation and altered mitochondrial function, only ORF3a and ORF9c induced a marked structural change in mitochondrial cristae (11)

Liu, Y.-Y

The combined mutational effects were examined for amylin receptor ECD binding