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The Janus kinase 2 and c-Jun N-terminal kinase pathways regulate HIF-1 regulation via adenosine monophosphate-activated protein kinase (AMPK) in response to H 2 O 2

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When combined with liver malignancies, cirrhosis accounts for 3.5% of all deaths worldwide (Asrani et al., 2019)

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Hseu YC, Vudhya Gowrisankar Y, Chen XZ, Yang YC, Yang HL

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reported that Asp and Asn in colon cancer cell lines could inhibit their activities by binding to LKB1 (encoding filament, threonine kinase, and direct phosphorylation of protein products to activate AMPK), thus inhibiting AMPK-mediated p53 activation

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[DOI] [PubMed] [Google Scholar] Noctor G, Mhamdi A, Chaouch S, Han Y, Neukermans J, Marquez-Garcia B, Queval G, Foyer CH

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