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The reported adverse events were limited to transient injection site edema, pain, pruritus, and erythema, and no serious or prolonged complications were identified

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Adrenal insufficiency: Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use

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Fibroids have both smooth muscle and fibroblast components, in addition to a substantial amount of fibrous extracellular matrix, which all contribute to the pathogenetic process

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