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The compound is a controlled substance in some jurisdictions due to its dopaminergic activity
A deficiency can also cause a condition called megaloblastic anemia which creates larger, immature, and abnormal red blood cells and leads to impaired DNA synthesis
Genomic instability and impaired DNA repair Lower NAD+ levels make our genome less stable through several mechanisms
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The loading phase builds melanin
instead, it indirectly affects NAD+ by inhibiting an enzyme called NNMT (nicotinamide N-methyltransferase)
