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N., Hu, S., Rowen, T

The pathways regulated by PKM2 in the nucleus are often associated with the mechanism of MDR phenotype formation, and some studies have also shown that the nonmetabolic enzyme function of PKM2 can promote drug resistance in tumor cells

C., Kuo, C

Notably, another recent study showed that AC-like tumor cells in diffuse intrinsic pontine glioma have a metabolic vulnerability to ferroptosis (Mbah et al, 2022)
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Weber T Polyketide Bioderivatization Using the Promiscuous Acyltransferase KirCII