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The leaves are also useful as a diuretic and aperients (laxatives)

Time to onset of symptoms and lab abnormalities varied from 14 to 540 days

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This therapeutic network was i) validated by two independent treatment datasets of patients with depression and a prospective preclinical experiment on male rats, ii) associated with networks of depression-related genes, neurotransmitters, and cognitions, and iii) also the target network of deep brain stimulation and repetitive transcranial magnetic stimulation (rTMS)