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Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis

HO-1 may indirectly affect FSP1 function by regulating intracellular iron levels, as it is the key enzyme for heme degradation (126)

28 Improved NF-B signaling drives the expression of target genes, including mucin 5AC, oligomeric mucus/gel-forming (MUC5AC) that is known worsening COPD pathogenesis via inducing mucus obstruction

In silico modeling of metabolic state in single Th17 cells reveals novel regulators of inflammation and autoimmunity

Furthermore, exosome-derived circTRPS1 from bladder cancer (BCa) cells could regulate intracellular ROS homeostasis and promote CD8 T cell depletion via the circTRPS1/miR141-3p/GLS1 axis [99]