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For example, it was demonstrated that LIP supports anchorage-independent growth of breast epithelial cells through suppression of anoikis, a form of programmed cell death that occurs in anchorage-dependent cells when they detach from the surrounding ECM, which is a prerequisite for metastasis formation 36

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Exosomes produced by tumors, commonly referred to as tumor-derived exosomes (TDEs), play a pivotal role in various cancer-related processes, including the remodeling of the tumor microenvironment (TME), angiogenesis, invasion, metastasis, and the development of resistance to treatment [24]

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Our real-time oxygen consumption rate (OCR) measurement studies revealed reduced basal OCR, the sum of all physiological mitochondrial oxygen consumption, in an isolated mitochondria preparation from the hearts of METH-treated mice compared to those of the vehicle-treated group (Fig

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However, some patients report sleep disturbances that may be indirectly related to gastrointestinal symptoms or metabolic changes during treatment

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