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Some research community protocols combine 5-Amino-1MQ with AOD-9604 (fat oxidation) or with a GLP-1 drug like semaglutide (appetite suppression), since the mechanisms do not overlap

Both are easy to add to a routine lab order

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Its main effects center on adipose tissue and cellular energy: It inhibits NNMT, which raises NAD+ availability and improves mitochondrial performance

5-Amino-1MQ before and after is ideal for anyone looking to improve their results in this area

In the STEP 1 trial, semaglutide led to an average 14.9% reduction in body weight over 68 weeks , far outperforming placebo (NEJM study on semaglutide for weight loss)