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Folate Metabolism in Neurodegeneration Neurodegenerative diseases are a growing concern worldwide, with conditions such as Alzheimers disease (AD) and Parkinsons disease (PD) becoming more common [290]

Sugatani J, Yamakawa K, Yoshinari K, Machida T, Takagi H, Mori M et al

Colloids and Surfaces B: Biointerfaces, 112 , 255263

doi: 10.1093/jxb/eri086 87 LeeJ.FengJ.CampbellK

Mechanistic reviews by Chelakkot et al., published in Experimental & Molecular Medicine (2018) , describe how dysregulation of these junctions is associated with increased intestinal permeability and immune activation

Studies have explored its potential effects on: Gastric ulcers Intestinal injury Tissue regeneration Inflammatory conditions While these findings are intriguing, large-scale human clinical trials are still lacking
