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published a landmark study in Nature Communications showing that MOTS-c treatment could double treadmill running capacity in old mice, restoring physical performance to levels seen in animals a fraction of their age

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doi: 10.1074/jbc.M703091200 88 FrancoR.SchoneveldO

Therefore, it is not surprising that dramatically greater global tyrosine phosphorylation is seen in PMA-stimulated Gsr / neutrophils than in yeast- or PMA-treated macrophages (Fig