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When cell membranes are exposed to various stimuli, vast amounts of AA are released from PLs by phospholipase A2 (PLA2) and phospholipase C (PLC) [54,55,56], which is then metabolized into biologically active inflammatory mediators like eicosanoids prostaglandin (PG), interleukin (IL), tumor necrosis factor (TNF), and leukotriene (LT)

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Alicia Zellmer, MD, and Joy Liu, MD, are resident physicians in internal medicine and members of the ABC News Medical Unit.

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Obese mice exhibited lower baseline expression of 3-AR in both fat types compared to lean controls