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Notably, most of the affinity to the binding site was still maintained
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J Biomed Mater Res A 73(3):320331
Approximately 15 participants will be enrolled in 2 sub-cohorts to receive 10 weeks of once-daily open-label induction treatment with SER-301 following 6 days of vancomycin pre-conditioning (125mg oral capsules, 4 times daily)
This is thought to be due to the presence of SOD1 in the mitochondrial membrane gap (Sharma et al., 2016)
