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Cellular redox status presents broad implications with diverse physiological and pathological processes
Research shows that in senescent cells, p53 levels are maintained low through ubiquitination while its pro-apoptotic activity is repressed through nuclear segregation by FOXO4. The peptide's competitive inhibition restores p53 activity by promoting nuclear exclusion, allowing p53 to execute its pro-apoptotic program and eliminate senescent cells through targeted pathway activation
In recent years, and particularly associated with the increase of cancer patients life expectancy, the occurrence of cancer treatment sequelae, including co...
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In addition, a series of oxidative phosphorylation inhibitors play important roles in decreasing the proliferation of CLL cells
Explore the liver anatomy, functions, diseases & prevention tips for a healthy liver
