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PDX1 is the cornerstone of pancreatic -cell functions and identity

This divergence presents potential therapeutic vulnerability, as it may allow the selective targeting of cancer cells by disrupting their reliance on proteostasis mechanisms

Nature 500 (7460), 102106

This represents a detrimental phenomenon observed in patients with poor response to subsequent therapies

lipids include the fatty droplets that naturally occur in the cytoplasm as well as the class of compounds which contain long-chain aliphatic hydrocarbons and their derivatives such as fatty acids, alcohols, amines, amino alcohols, and aldehydes

In: Wolff K, Lowell AG, Stephen I (eds)