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Les diffrents seuils de concentration auxquels apparaissent les diffrents effets de l'acroline sont les suivants : perception d'une odeur, 0,007 mg/m 3 , irritation oculaire, 0,3 mg/m 3 , irritation du nez et clignement des yeux, 0,03 mg/m 3 , rduction de la frquence respiratoire, 0,7 mg/m 3

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The clinical potential of this approach is underscored by the approval of istradefylline in Japan and the United States as an adjunct therapy for PD patients experiencing motor fluctuations, representing the most advanced A 2A receptor antagonists in clinical development [480482]

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Therefore, plasma Hcy concentration can be significantly increased in the deficiency of essential cofactor Vitamin B12/B6 or cosubstrate folate ( 3.3

3 Characterization of nanomembrane temperature sensor integrated in P-CARE needle