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Age, Charlson Comorbidity Index (CCI) score, profile of hospital department (medical (MD), surgical or ICU) where CDI was diagnosed, type of CDI (healthcare-associated (HA), hospital or community-acquired) and rate of risk factors (RF) have been estimated in both 2011 and 2015

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Animal model and treatment Age-matched male BALB/c nude mice (46 weeks old) were used for the orthotopic mouse model

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doi: 10.1016/S0009-3084(99)00071-7 52 SilvaLCFutermanAHPrietoM

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Serum concentrations were coupled with Bcell kinetics to predict drug effect

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