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Congruently, elevated and sustained plasma levels of CRP have been observed in healthy humans after prolonged sleep deprivation (5 or 10 nights), in concomitance with increased heart rate 190,203 , lymphocyte pro-inflammatory activation, and production of cytokines (e.g., IL-1, IL-6, and IL-17) 203

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2000), risperidone might further help to reduce the inflammation that is often seen in PTSD and thus prevent the vicious cycle of inflammation-induced mitochondrial dysfunction

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