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(4) The researchers investigated cell culture models of fibrosis, which also expressed senescence markers such as more -galpositive cells and higher p16 and p21

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Because studies have evaluated GHK-Cu across multiple cell types (including fibroblasts and keratinocytes) and in preclinical models, it is commonly used to support mechanistic work on aging-related tissue changes, repair biology, and copper homeostasisstrictly within controlled research designs

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