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Sommermeyer D, Hudecek M, Kosasih PL, Gogishvili T, Maloney DG, Turtle CJ, et al

4.6 Relationship between cholinergic system abnormalities and ferroptosis in AD 4.6.1 Relationship between abnormal acetylcholine synthesis/degradation and ferroptosis in AD Cholinergic neurons are widely distributed in the human brain and play crucial roles in neurogenesis, neuronal differentiation, and synaptic plasticity (Long and Holtzman, 2019)

Endocrine System: Diabetes Mellitus Dysfunction of insulin production and secretion, as well as the target cells responsiveness to insulin, can lead to a condition called diabetes mellitus

Metabolic reactions Glutamic acid (or glutamate) is involved in several important metabolic reactions in the body

doi:10.1111/j.1365-3164.2007.00647.x

Recent advances in single-cell and spatial omics have enabled high-resolution dissection of ferroptotic mechanisms in neurodegeneration